Betting against the Tennessee Titans has been a profitable NFL betting strategy this season. Tennessee is 2-9 against the spread, but the Titans are coming off an impressive victory on the road against the Houston Texans as 7.5-point underdogs. This week, the Titans will take on the Washington Commanders on Sunday. The Commanders lost at home against the Dallas Cowboys last week, 34-26, as double-digit favorites. According to the latest Week 13 NFL odds, Washington is a 5.5-point home favorite against Tennessee. Other Week 13 NFL spreads of note include Steelers vs. Bengals (-2.5, 47), Eagles vs. Ravens (-2.5, 50.5) and 49ers vs. Bills (-7, 46). If you are looking for NFL picks, NFL parlays, Fantasy football rankings or NFL DFS picks for Week 13, SportsLine has you covered with its proven model, AI PickBot, and team of experts. They even have one pick that returns a whopping +14000, so be sure to see what they have to say.

Self-learning AI reveals top NFL picks

SportsLine AI hit a whopping 2,029 4.5- and 5-star sports betting picks since the start of last season. Now it is back with its picks on the spread, money line and total for each Week 13 NFL game. It is backing the New England Patriots to pull off the upset as 2.5-point underdogs at home against the Indianapolis Colts in a game with an over/under of 42.5. See AI picks for each Week 13 NFL game right here.

NFL parlay picks could generate massive payouts

SportsLine’s model has returned well over $7,000 on top-rated picks since its inception, so those picks can confidently be used to fill out NFL parlay picks on betting apps. The model has built a five-team parlay for Week 13 that pays 25-1, and one of the legs is Washington (-5.5, 43.5) to cover at home against Tennessee. The Commanders cover the spread in 60% of simulations, and the rest of the five-team parlay can be found here. 

Fantasy rankings to help you win your matchups

SportsLine’s model simulates every game 10,000 times, which has helped it produce better Fantasy rankings than human experts over the last few seasons. It has revealed its Week 13 Fantasy football positional rankings that can be used to make start-sit decisions. Broncos quarterback Bo Nix is projected to be a top-10 quarterback this week, and it also has full rankings for every position right here. 

The Week 13 Fantasy football waiver wire is loaded with players capable of making an impact this week and the remainder of the season. SportsLine’s R.J. White breaks down the best widely available Fantasy football free agents heading into Week 13, helping you find the top options at every position rostered in fewer than 60% of leagues on CBSSports.com. See them all right here. 

NFL DFS picks from top experts 

SportsLine has a DFS Optimizer that simulates every game 10,000 times and uses info from the SportsLine Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks/plays for any slate on sites like FanDuel and DraftKings. See the top picks for both showdown and classic game formats and get the optimizer’s complete Week 13 NFL DFS rankings right here. 

SportsLine’s Jimmie Kaylor is an NFL and DFS expert, who opened the 2022 NFL season by winning DraftKings‘ NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. He’s analyzed the Thanksgiving NFL DFS slate and locked in his top selections, which include Lions running back Jahmyr Gibbs. See his NFL DFS advice for Thursday’s NFL slate right here. 

Advanced NFL model simulates every game 10,000 times 

SportsLine’s model enters Week 13 of the 2024 NFL season on an incredible 22-8 betting hot streak on top-rated NFL picks this year. Longer term, it is on a 202-136 roll on top-rated NFL picks that dates back to the 2017 season and a 56-29 roll on top-rated NFL picks since Week 7 of 2022. The model has revealed picks for every game in Week 13, and one of its favorite picks is the Saints (+2.5, 47.5) covering at home against the Rams on Sunday, which cashes in well over 70% of simulations. You can find the model’s picks for every game here. 

NFL Vegas expert picks revealed 

SportsLine has an expansive team of NFL experts who provide quality betting advice for every game on the schedule. Insider R.J. White (21-10-1 over his last 32 NFL ATS picks) has revealed his best bets for Week 13, including the Bengals (-2.5) to cover at home against the Steelers in a game that opened at Cincinnati -5.5. White’s NFL best bets for Week 13 can be found here.

Eric Cohen, who is 88-42 since Week 4, has exact score predictions for all 16 games. He is high on the Bills (-7, 46) to beat the 49ers soundly at home on Sunday night, and is also calling for an underdog to pull off a surprising upset. Hit any of his exact score picks and you’re looking at a payout well over 100-1. That pick, along with his prediction for every game, is available here. SportsLine’s advanced computer model has also locked in its exact score predictions for every Week 13 NFL game right here. 

2024 NFL Thanksgiving Day picks, best bets, start times

Chicago Bears vs. Detroit Lions (12:30 p.m. ET)

The Detroit Lions will play on Thanksgiving Day for the 85th straight season when they host the rival Chicago Bears in an NFC North matchup at 12:30 p.m. ET. SportsLine’s model likes the Over (48) in that game, calling for 51 total points, and has also revealed its picks on the spread and money line. NFL expert Larry Hartstein, who is on a 98-63 roll (+2324) on his NFL picks, has analyzed this matchup from every angle and locked in his best bet for Lions vs. Bears right here.

SportsLine’s AI PickBot has locked in its player props for players like Jared Goff, Caleb Williams and Amon-Ra St. Brown. One of its top picks is Goff going Over 243.5 passing yards, which has earned a five-star rating. The AI PickBot is calling for Goff to finish with 292.2 passing yards on average, providing plenty of value. You can see all the top-rated NFL prop picks from the AI PickBot here. 

New York Giants vs. Dallas Cowboys (4:30 p.m. ET)

An NFC East rivalry takes place when the Dallas Cowboys host the New York Giants on Thanksgiving Day. SportsLine’s model has simulated this matchup 10,000 times and is leaning Over the total (39). It also projects one side of the spread hitting in well over 50% of simulations. See the model’s top picks right here. NFL expert Larry Hartstein, who is on a 27-10 roll on Cowboys games, has analyzed this matchup from every angle and just locked in his best bet for Cowboys vs. Giants right here.

SportsLine’s AI PickBot has locked in its player props for players like CeeDee Lamb, Cooper Rush, Malik Nabers and Rico Dowdle. One of its top picks is Lamb finishing Over 66.5 receiving yards, which has earned a five-star rating. The AI PickBot is calling for Lamb to finish with 86.4 receiving yards on average. You can see all the top-rated NFL prop picks from the AI PickBot here.

Miami Dolphins vs. Green Bay Packers (8:20 p.m. ET)

The Packers have won six of their last seven games and now they’ll take on the Miami Dolphins on Thanksgiving night. SportsLine’s model likes the Over (47.5) in that game, and has also revealed its picks on the spread and money line. NFL insider R.J. White, who is on a 73-30 roll on Packers games, has identified a critical X-factor that has him jumping all over one side of the spread. See that pick right here. 

SportsLine’s AI PickBot has locked in its player props for players like Jordan Love, Tua Tagovailoa, Tyreek Hill and Josh Jacobs. One of its top picks is Tagovailoa going Over 238.5 passing yards, which has earned a five-star rating. The AI PickBot is calling for Tagovailoa to finish with 286.2 passing yards on average, providing plenty of value. You can see all the top-rated NFL prop picks from the AI PickBot here.